Campus: UMD | Building: School of Public Health | Room: 2234H
Phone: (301) 405-2551 |
Office Hours: 

By Appointment


Dr. He's current research focuses on longitudinal data analysis, time-to-event data analysis, nonparametric and semiparametric methods, as well as applications in epidemiology, environmental health, and biomedical studies.

Active Research Funding:

Subcontract Principal Investigator: R01 AI119012 "Lubricant Use and the Vaginal Microbiome" via University of Maryland, Baltimore (Prime Sponsor: National Institute of Allergy and Infectious Diseases; PI: Brotman, R.M.)

Subcontract Principal Investigator: R01 AI116799 "Longitudinal Study of the Vaginal Microbiome Prior to Incident STI" via University of Maryland, Baltimore (Prime Sponsor: National Institute of Allergy and Infectious Diseases; PI: Brotman, R.M.)

Subcontract Principal Investigator: R01 HL116533 "Therapeutic Potential for Aldosterone Inhibition in Duchenne Muscular Dystrophy"via The Ohio State University (Prime Sponsor: National Heart, Lung, and Blood Institute; PIs: Rafael-Fortney, J.A. and Raman, S.V.)

Site Principal Investigator: "The Epidemiology of Concussions in Ivy League/Big Ten Sports: A Web-Based Registry" funded by The Council of Ivy League Presidents and The Big Ten Conference (Co-PI: Klossner, D.)

Editorial Boards:

Associate Editor, Lifetime Data Analysis

Editor-in-Chief, International Chinese Statistical Association (ICSA) Bulletin

Education and Training

2003-2007    Ph.D. in Statistics, University of Missouri
2000-2003    B.A. in Economics, Peking University, Beijing, China
1999-2003    B.S. in Statistics, Peking University, Beijing, China


EPIB 650: Biostatistics I (Syllabus)
EPIB 653: Applied Survival Data Analysis (Syllabus)
EPIB 655: Longitudinal Data Analysis (Syllabus)
EPIB 786: Capstone Project in Public Health
EPIB 798: Independent Study
EPIB 799: Master's Thesis Research
EPIB 898: Pre-Candidacy Research

Honors and Awards

ICSA Outstanding Service Award
International Chinese Statistical Association

Summer Research and Scholarship Award (RASA)
Graduate School, University of Maryland

Leda Amick Wilson Mentoring Award
School of Public Health, University of Maryland

Eighth Annual University-Wide Celebration of Scholarship and Research, University of Maryland

Delta Omega Public Health Honor Society

Doris W. Sands Excellent Teaching Award
School of Public Health, University of Maryland

Excellence in Teaching Award
College of Public Health, The Ohio State University

Best Contributed Paper Award
Winemiller 2008 Conference on Survival Analysis and Its Applications, University of Missouri

ENAR Distinguished Student Paper Award
International Biometric Society (Eastern North American Region)

ASA Section on Statistics in Epidemiology Travel Award (Student Paper Award)
American Statistical Association

ICSA Student Award (Student Paper Award)
International Chinese Statistical Association

Outstanding Performance on Doctoral Examinations Award
University of Missouri

G. Ellsworth Huggins Fellowship
Graduate School, University of Missouri


Google Scholar:

My Bibliography at NCBI:

(Selected from 50+ publications)

He, X., Feng, X., Tong, X., and Zhao, X. (2017). Semiparametric partially linear varying coefficient models with panel count data. Lifetime Data Analysis 23, 439-466.

O'Neal, C.R., Weston, L.C., He, X., Huang, K.-Y., Pine, D.S., Kamboukos, D., and Brotman, L.M. (2017). Change in depression from preadolescence to adolescence: The role of early anger socialization and child anger among low-income, ethnic minority families. Journal of Adolescence 59, 1-7.

Rosenberg Goldstein, R.E., Kleinfelter, L., He, X., Micallef, S.A., George, A., Gibbs, S.G., and Sapkota, A.R. (2017). Higher prevalence of coagulase-negative staphylococci carriage among reclaimed water spray irrigators. Science of the Total Environment 595, 35-40.

Kumar, V., Min, J.K., He, X., and Raman, S.V. (2017). Computation of calcium score with dual-energy computed tomography: A phantom study. Journal of Computer Assisted Tomography 41, 156-158.

Raman, S.V., Hor, K.N., Mazur, W., He, X., Kissel, J.T., Smart, S., McCarthy, B., Roble, S.L., and Cripe, L.H. (2017). Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: results of a two year open-label extension trial. Orphanet Journal of Rare Diseases 12, Article 39.

Li, Y., He, X., Wang, H., and Sun, J. (2016). Regression analysis of longitudinal data with correlated censoring and observation times. Lifetime Data Analysis 22, 343-362.

Yao, B., Wang, L., and He, X. (2016). Semiparametric regression analysis of panel count data allowing for within-subject correlation. Computational Statistics & Data Analysis 97, 47-59.

Nowak, R.G., Gravitt, P.E., He, X., Ketende, S., Dauda, W., Omuh, H., Blattner, W.A., Charurat, M.E.; TRUST Study Group. (2016). Prevalence of anal high-risk human papillomavirus infections among HIV-positive and HIV-negative men who have sex with men (MSM) in Nigeria. Sexually Transmitted Diseases 43, 243-248.

Jaschek, G., Carter-Pokras, O., He, X., Lee, S., and Canino, G. (2016). Association of child maltreatment and depressive symptoms among Puerto Rican youth. Journal Child Abuse & Neglect 58, 63-71.

Jaschek, G., Carter-Pokras, O.D., He, X., Lee, S., and Canino, G. (2016). Association of types of life events with depressive symptoms among Puerto Rican youth. PLOS ONE 11, Article e0164852.

He, X., Whitmore, G.A., Loo, G.Y., Hochberg, M.C., and Lee, M.-L.T. (2015). A model for time to fracture with a shock stream superimposed on progressive degradation: the Study of Osteoporotic Fractures. Statistics in Medicine 34, 652-663.

He, X., Chen, L., Lei, L., Xia, H.A., and Lee, M.-L.T. (2015). A simple method for estimating confidence intervals for exposure adjusted incidence rate and its applications to clinical trials. Journal of Biometrics & Biostatistics 6, Article 238.

Li, Y., He, X., Wang, H., Zhang, B., and Sun, J. (2015). Semiparametric regression of multivariate panel count data with informative observation times. Journal of Multivariate Analysis 140, 209-219.

Xiao, T., Whitmore, G.A., He, X., and Lee, M.-L.T. (2015). The R Package threg to implement threshold regression models. Journal of Statistical Software 66, 1-16.

Zang, C., He, X., and Liu, H. (2015). Selective disclosure of HIV status in egocentric support networks of people living with HIV/AIDS. AIDS and Behavior 19, 72-80.

Wu, F., He, X., Guida, J., Xu, Y., and Liu, H. (2015). Network stigma towards people living with HIV/AIDS and their caregivers: an egocentric network study in China. Global Public Health 10, 1032-1045.

Raman, S.V., Hor, K.N., Mazur, W., Halnon, N., Kissel, J.T., He, X., Tran, T., Smart, S.,  McCarthy, B., Taylor, M.D., Jefferies, J.L., Rafael-Fortney, J.A., Lowe, J., Roble, S.L., and Cripe, L.H. (2015). Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, placebo-controlled trial. The Lancet Neurology 14, 153-161.

Raman, S.V., Sharkey-Toppen, T.P., Tran, T., Liu, J.X., McCarthy, B., He, X., Smart, S., Gulati, M., Wexler, R., Simonetti, O.P., and Jackson, R.D. (2015). Iron, in ammation and atherosclerosis risk in men vs. perimenopausal women. Atherosclerosis 241, 249-254.

Shaw, K.S., Sapkota, A.R., Jacobs, J.M., He, X., and Crump, B.C. (2015). Recreational swimmers' exposure to Vibrio vulnificus and Vibrio parahaemolyticus in the Chesapeake Bay, Maryland, USA. Environment International 74, 99-105.

He, X., Lu, X., Chen, S., Hochberg, M.C., and Lee, M.-L.T. (2014). Association between obesity, race and knee osteoarthritis: The Multicenter Osteoarthritis Study. International Journal of Statistics in Medical Research 3, 224-230.

Brotman, R.M., He, X., Gajer, P., Fadrosh, D., Sharma, E., Mongodin, E.F., Ravel, J., Glover, E.D., and Rath, J.M. (2014). Association between cigarette smoking and the vaginal microbiota: a pilot study. BMC Infectious Diseases 14, 471.

Liu, H., He, X., Levy, J., Xu, Y., Zang, C., and Lin, X. (2014). Psychological impacts among older and younger people living with HIV/AIDS in Nanning, China. Journal of Aging Research, 576592.

Crouser, E.D., Ono, C., Tran, T., He, X., and Raman, S.V. (2014). Improved detection of cardiac sarcoidosis using magnetic resonance with myocardial T2 mapping. American Journal of Respiratory and Critical Care Medicine 189, 109-112.

He, X. and Whitmore, G.A. (2013). Connecting threshold regression and accelerated failure time models. In Risk Assessment and Evaluation of Predictions, M.-L. T. Lee, M. Gail, R. Pfeiffer, G. Satten, T. Cai, and A. Gandy (Ed.), New York: Springer, 47-60.

Lee, S., Chen, L., He, X., Miller, M.J., and Juon, H.-S. (2013). A cluster analytic examination of acculturation and health status among Asian Americans in the Washington DC metropolitan area, United States. Social Science & Medicine 96, 17-23.

Fransen, M., Pérodin, J., Hada, J., He, X., and Sapkota, A. (2013). Impact of vehicular strike on particulate matter air quality: Results from a natural intervention study in Kathmandu valley. Environmental Research 122, 52-57.

Wu, T.T. and He, X. (2012). Coordinate ascent for penalized semiparametric regression on high-dimensional panel count data. Computational Statistics and Data Analysis 56, 25-33.

Xiao, T., Whitmore, G.A., He, X., and Lee, M.-L.T. (2012). Threshold regression for time-to-event analysis: The stthreg package. Stata Journal 12, 257-283.

Shah, S.,Weed, H.G., He, X., Agrawal, A., Ozer, E., and Schuller, D.E. (2012). Alcohol-related predictors of delirium after major head and neck cancer surgery. Archives of Otolaryngology - Head & Neck Surgery 138, 266-271.

Jordan, R., Lingen, M., Perez-Ordonez, B., He, X., Pickard, R., Inman, A., Koluder, M., Jiang, B., Wakely, P., Xiao, W., and Gillison, M.L. (2012). Validation of methods for oropharyngeal cancer HPV status determination in US cooperative group trials. The American Journal of Surgical Pathology 36, 945-954.

Pickard, R., Xiao, W., Broutian, T.R., He, X., and Gillison, M.L. (2012). The prevalence and incidence of oral human papillomavirus infection among young men and women, age 18-30 years. Sexually Transmitted Diseases 39, 559-566.

Rosenberg Goldstein, R.E., Micallef, S.A., Gibbs, S.G., Davis, J.A., He, X., George, A., Kleinfelter, L.M., Schreiber, N.A., Mukherjee, S., Sapkota, A., Joseph, S.W., and Sapkota, A.R. (2012). Methicillin-resistant staphylococcus aureus (MRSA) detected at four U.S. wastewater treatment plants. Environmental Health Perspectives 120, 1551-1558.

He, X. (2011). Comments on: Nonparametric inference based on panel count data. TEST 20, 46-47.

Broutian, T.R., He, X., and Gillison, M.L. (2011). Automated high throughput DNA isolation for detection of human papillomavirus in oral rinse samples. Journal of Clinical Virology 50, 270-275.

Mihai, G., He, X., Zhang, X., McCarthy, B, Tran, T., Pennell, M.L., Blank, J., Simonetti, O.P., Jackson, R.D., and Raman, S.V. (2011). Design and rationale for the study of changes in iron and atherosclerosis risk in perimenopause. Journal of Clinical & Experimental Cardiology 2, 152.

He, X. and Lee, M.-L.T. (2010). First-hitting-time based threshold regression. In International Encyclopedia of Statistical Science, M. Lovric (Ed.), New York: Springer, 523-524.

Anderson, S.E., He, X., Schoppe-Sullivan, S. and Must, A. (2010). Externalizing behavior in early childhood and body mass index from age 2 to 12 years: longitudinal analyses of a prospective cohort study. BMC Pediatrics 10, 49.

Raman, S.V., Simonetti, O.P., Winner III, M.W., Dickerson, J.A., He, X., Mazzaferri Jr, E.L., and Ambrosio, G. (2010). Cardiac magnetic resonance with edema imaging identifies myocardium at risk and predicts worse outcome in patients with non-ST-segment elevation acute coronary syndrome. Journal of the American College of Cardiology 55, 2480-2488.

He, X., Tong, X., and Sun, J.  (2009). Semiparametric analysis of  panel count data with correlated observation and follow-up times. Lifetime Data Analysis 15, 177-196.

Tong, X., He, X. (corresponding author), Sun, L., and Sun, J. (2009).  Variable selection for panel count data via non-concave penalized estimating function. Scandinavian Journal of Statistics 36, 620-635.

He, X., Tong, X., Sun, J., and Cook, R. (2008). Regression analysis of multivariate panel count data. Biostatistics 9, 234-248.

Tong, X., He, X., Sun, J., and Lee, M.-L.T. (2008). Joint analysis of current status and marker data: an extension of a bivariate threshold model. The International Journal of Biostatistics 4, Article 21.

Sun, J., Tong, X., and He, X. (2007). Regression analysis of panel count data with dependent observation times. Biometrics 63, 1053-1059.