Sarah Kuzmiak-Glancy
Dr. Kuzmiak-Glancy is a lifelong athlete who has merged her love of playing sports with her research focus. After studying Exercise Physiology as an undergraduate at Rutgers University, she became captivated by mitochondrial energetics during her PhD at Arizona State University. Dr. Kuzmiak-Glancy’s research focuses on determining how skeletal and cardiac mitochondrial energy production is exquisitely matched to energy demand and how this coordination is altered during exercise and in disease.
Departments/Units
Areas of Interest
Core FacultyHeart and Skeletal Muscle Metabolism; Mitochondrial Function; Exercise Physiology
Postdoctoral Training, National Lung, Blood, 2016
Heart Institute National Institutes of Health
Postdoctoral Training, Biomedical Engineering, 2012-2016
George Washington University
PhD, Biology, 2012
Arizona State University
BS, Exercise Science, 2008
Rutgers University
KNES 360 Exercise Physiology
KNES 464 Exercise Metabolism
KNES 691 Muscular Aspects of Exercise Physiology
Maryland Research Excellence Celebration Honoree, University of Maryland, 2020
Mamie Doud Eisenhower Memorial Award, American Heart Association, 2015
Giles, A.V., J. Sun, A.N. Femnou, S. Kuzmiak-Glancy, J.L. Taylor, R. Covian, E. Murphy, R.S. Balaban. (2018) “Paradoxical arteriole constriction compromises cytosolic and mitochondrial oxygen delivery in the isolated saline-perfused heart.” Am J Physiol Heart Circ Physiol 315: H1791-H1804
Kuzmiak-Glancy, S., R. Covian, A.N. Femnou, B. Glancy, R. Jaimes III, A. Wengrowski, K. Garrott, S.A. French, R.S. Balaban, M.W. Kay. (2018). “Cardiac performance is limited by oxygen delivery to the mitochondria in the crystalloid-perfused heart.” Am J Physiol Heart Circ Physiol 314: H704-H715.
Femnou, A.N., S. Kuzmiak-Glancy, R. Covian, A.V. Giles, M.W. Kay, R.S. Balaban. (2017). “Intracardiac light catheter f rapid scanning transmural absorbance spectroscopy of perfused myocardium: measurement of myoglobin oxygenation and mitochondrial redox state.” Am J Physiol Heart Circ Physiol 313: H1199-H1208.
Moreno, A., S. Kuzmiak-Glancy, R. Jaimes III, M.W. Kay. (2017). "Enzyme-dependent recovery of NADH after phobleaching to assess dehydrogenase activity of isolated perfused hearts.” Scientific Reports 7: 45744.
Garrott, K., S. Kuzmiak-Glancy, A. Wengrowski, H. Zhang, J. Rogers, M.W. Kay. (2017). “KATP channel inhibition blunts electromechanical decline during hypoxia in left ventricular working rabbit hearts.” J Physiol 5959(12): 3799-3813.
Willis, W.T., M.R. Jackman, J.I. Messer, S. Kuzmiak-Glancy, B. Glancy. (2016) “A simple hydraulic analog model of oxidative phosphorylation.” Med Sci Sports Exerc 48: 990-1000.
Kuzmiak-Glancy, S., R Jaimes III, A.M. Wengrowski, M.W. Kay. (2015) “Oxygen demand of perfused heart preparations: How electromechanical function and inadequate oxygenation affect physiology and optical measurements.” Exp Physiol 100: 603–616.
Jaimes III, R.J., S. Kuzmiak-Glancy, D.M. Brooks, L.M. Swift, N.G. Posnack, M.W. Kay. (2015) “Functional response of the isolated, perfused heart to pyruvate dehydrogenase activation by dichloroacetate and pyruvate.” Pflugers Archiv Eur J of Physiol pg 1-12.
Kuzmiak-Glancy, S., W.T. Willis. (2014) “Skeletal muscle fuel selection occurs at the mitochondrial level.” J Exp Biol 217: 1993-2003.
Kuzmiak, S., B. Glancy, K.L. Sweazea, W.T. Willis. (2012) "Mitochondrial function in sparrow pectoralis muscle." J Exp Biol 215: 2039-2050.